Some lack the small chest appendages of the Slashers, but their talons are much larger. Their heads, legs, and bodies retain a vaguely human form, albeit much chunkier and muscular than Slashers (likely due to the fact that the infected soldiers or security personnel tend to be more well-built than civilians). Their design is similar to that of a Slasher however, this is hard to notice due to their speed.

Their name is derived from their constant twitching and spasmodic behavior. They also make distinctive jabbering noises when they get close. Due to their incredible speed, they are very capable of dodging Isaac's weapons in harder difficulties when they see it coming. It also causes them to have highly erratic and spastic movements, and their features seem to blur as they move when seen close up. Because of the reversed Stasis Module merged into their bodies, Twitchers can react and move several times faster than any other Necromorph variant, making them very hard to hit before they close in to melee range. They are physically similar to Slashers in most aspects.Ī disturbing side-effect of the transformation is that the Stasis modules become fused with the resulting creature, and the effect of the Stasis Module are strangely reversed, with terrifying results.

The Twitchers are the result of the Necromorph infection converting the corpses of people who were equipped with built-in Stasis Modules (such as soldiers, security personnel or special division scientists).

Dead space concept art necromorph